QuickView for interleukin 6 receptor;jsessionid=834D1A00E6337B18DF9D9C2447DD20EF (gene)
- Gene Symbol:
- Il6ra
Mus musculus - Full name:
- interleukin 6 receptor, alpha
- Synonyms:
- CD126, IL-6R, IL-6R-alpha, IL-6RA, Il6r, interleukin-6 receptor subunit alpha, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha
- Genomic Location:
- Chr 3: 89673246-89717084
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cytokine binding | transmembrane signaling receptor activity | enzyme binding | ciliary neurotrophic factor binding | signaling receptor binding | ciliary neurotrophic factor receptor activity | cytokine receptor binding | growth factor binding | molecular function regulator | interleukin-12 binding | interleukin-12 alpha subunit binding | signaling receptor activity | identical protein binding | cytokine receptor activity | protein binding | protein homodimerization activity | receptor regulator activity | protein dimerization activity | growth factor activity | interleukin-6 receptor activity | receptor ligand activity | interleukin-23 receptor binding | interleukin-6 binding | growth factor receptor binding | interleukin-6 receptor binding | interleukin-12 receptor binding
GO Biological Process
positive regulation of immune response | positive regulation of smooth muscle cell proliferation | response to cytokine | interleukin-6-mediated signaling pathway | negative regulation of collagen biosynthetic process | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | positive regulation of lymphocyte activation | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | ciliary neurotrophic factor-mediated signaling pathway | cellular process | developmental growth | positive regulation of adaptive immune response | positive regulation of protein kinase activity | positive regulation of catalytic activity | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of immune response | regulation of cellular process | regulation of metabolic process | positive regulation of activated T cell proliferation | positive regulation of interferon-gamma production | positive regulation of cellular protein metabolic process | regulation of natural killer cell activation | endocrine pancreas development | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of JAK-STAT cascade | positive regulation of lymphocyte proliferation | regulation of activation of Janus kinase activity | regulation of cell proliferation | ciliary neurotrophic factor receptor activity | positive regulation of cell-cell adhesion | positive regulation of cell activation | positive regulation of natural killer cell activation | positive regulation of T cell activation | negative regulation of metabolic process | regulation of cell adhesion | molecular function regulator | cellular response to interleukin-6 | positive regulation of mononuclear cell proliferation | system development | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | regulation of collagen biosynthetic process | regulation of catalytic activity | regulation of phosphorylation | regulation of T cell activation | regulation of activated T cell proliferation | pancreas development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | cellular response to cytokine stimulus | positive regulation of NK T cell activation | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | positive regulation of chemokine production | endocrine system development | cytokine receptor activity | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of tyrosine phosphorylation of STAT protein | regulation of collagen metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | regulation of JAK-STAT cascade | regulation of kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | regulation of adaptive immune response | positive regulation of leukocyte activation | interleukin-6 receptor activity | receptor ligand activity | positive regulation of interleukin-6 production | positive regulation of T-helper 1 type immune response | negative regulation of biosynthetic process | animal organ development | regulation of cell activation | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of cytokine production | positive regulation of MAPK cascade | regulation of cell communication | signaling | regulation of T cell proliferation | positive regulation of phosphorylation | regulation of cytokine production | developmental process | positive regulation of alpha-beta T cell activation | regulation of chemokine production | regulation of cell-cell adhesion | positive regulation of metabolic process | regulation of interferon-gamma production | cellular response to organic substance | regulation of smooth muscle cell proliferation | response to interleukin-6 | regulation of interleukin-6 production | positive regulation of leukocyte cell-cell adhesion | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of activation of Janus kinase activity | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | ciliary neurotrophic factor receptor complex | apical plasma membrane | somatodendritic compartment | cell body | cell | interleukin-12 complex | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | external side of plasma membrane | receptor complex | interleukin-23 complex | apical part of cell | protein-containing complex | plasma membrane | neuronal cell body membrane | integral component of plasma membrane | extracellular region | interleukin-6 receptor complex | extracellular space | cell periphery | cell body membrane | cell surface | membrane | intrinsic component of plasma membrane
